Five tools, one way of working: show the basis.

A consultation, start to finish

Consultations run in the background and take a minute or two, which is one more reason HealthDefence is not for decisions that cannot wait.

Verify a diagnosis

A reasoned second opinion on the diagnosis you propose.

How it works

• Three to six specialist reviewers (Claude Sonnet), chosen for the presentation, each give an opinion; a judge (Claude Opus) weighs them against a written rubric, with up to three rounds of deliberation when they disagree.
• The verdict comes with its reasoning, the dissenting views, and the cited passages it relied on.

What it relies on

Age, sex, presenting symptoms and duration, history, current medications, allergies, vital signs, discrete laboratory results, and your proposed diagnosis.

Limits

The council reasons from what you enter; it has not examined the patient. Its confidence figure is the models' own estimate, not a calibrated probability.

Generate a differential

A differential diagnosis from the presentation.

How it works

• The same council works from the presentation alone and returns a differential, each item with the tests that would confirm or exclude it.
• Every item cites the passages behind it, and the result lists the case inputs that were not entered.

What it relies on

The same clinical information as Verify, without a proposed diagnosis.

Limits

A differential is a list to work through, not a diagnosis. Missing inputs narrow what the council can consider.

Medication safety

Each medication's current FDA label, read against your patient.

How it works

• Each label is fetched from openFDA at the time of the request (names resolved through NLM RxNav). Only drug names leave our systems for this look-up.
• One model pass reads the labels against the patient's conditions, allergies, other medications and laboratory values; a second pass reviews those findings.
• Every quoted label sentence is checked, by exact text match, to occur in that label. Findings whose quote cannot be confirmed are shown separately and marked as unconfirmed.

What it relies on

The medication list, plus conditions, allergies, age, pregnancy status, kidney and liver function and relevant laboratory values when you have them.

Limits

A medication with no FDA label (for example some supplements) is listed as not checked. The analysis covers what the labels say; it does not give treatment directives.

Lab results

Discrete results read against the reference range, and what they mean together.

How it works

• Each result's status (low, high, critical) is computed by fixed rules against the range you entered, or a typical range marked as such. No model decides it.
• Findings across results are written by a model, grounded in the clinical corpus, with every quote checked against its source. A critical value raises a notice at the top.

What it relies on

Discrete results (one value per test, with units and ideally the laboratory's own reference range), plus age, sex, conditions and medications.

Limits

One value per test: trends over time are not interpreted. Troponin and CK-MB are not interpreted, because they bear on time-critical decisions.

Equivalent products

Therapeutically equivalent products, from the official registers.

How it works

• US equivalence comes from the FDA Orange Book therapeutic-equivalence codes (A-rated products; AB1 and AB2 kept apart; FDA's special cases shown with FDA's own note).
• Spanish equivalence comes from the AEMPS CIMA register (same active ingredients, strength, dosage form and route; products marked "no sustituible" are flagged).
• The source and the date of its data are shown with every answer. A US product and a Spanish product are never presented as equivalent to each other.

What it relies on

A product or ingredient name, with strength and dosage form when you know them.

Limits

Only what the two registers record. Over-the-counter monograph products have no Orange Book entry.

Accept, sign, export

When you accept a consultation, HealthDefence drafts the paperwork for you to review.

• A case note signed by you, with the basis of the decision.
• A consent record for the consultation.
• A FHIR R4 Bundle, checked in our test suite with HL7's official FHIR validator against the US Core profiles.
• US by default, with a Spanish variant for the EU pilot.